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PateikėInge Atmadjaja
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RNR polimerazės III promotoriai
Jungiasi TFIIIA Jungiasi TFIIIC Jungiasi TFIIIC Jungiasi TFIIIC TFIIIA ir TFIIIC padeda prisjungti TFIIIB transkripcijos faktoriui
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RNR polimerazės II promotoriai
Šis promotorius dažniausiai naudojamas embrioninio vystymosi metu
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Kompleksą gali sudaryti virš 85 polipeptidų
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Removes acetyl groups, thereby restoring a tighter interaction
1. Covalent modification of histones Amino terminals of histones are modified in various ways Acetylation; phosphorylation; methylation Adds acetyl groups, thereby loosening the interaction between histones and DNA Removes acetyl groups, thereby restoring a tighter interaction
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2. ATP-dependent chromatin remodeling
The energy of ATP is used to alter the structure of nucleosomes and thus make the DNA more accessible Proteins are members of the SWI/SNF family Acronyms refer to the effects on yeast when these enzyme are defective Mutants in SWI are defective in mating type switching Mutants in SNF are sucrose non-fermenters These effects may significantly alter gene expression
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Skirtingų organizmų SWI/SNF kompleksai
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Chromatino surinkimo ir transkripcinės aktyvacijos, dalyvaujant SWI–SNF, modelis
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